Description

(5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate (API intermediate) with the CAS number 2703756-83-4. This compound is a critical building block in modern medicinal chemistry, valued for its unique halogenated and cyclopropyl-substituted aromatic amine structure. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core building block in multi-step synthesis routes for complex target molecules.
• CNS Drug Development: The structural motif is relevant for compounds targeting neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other anti-cancer agents.
• Chemical Biology: Used as a probe or labeled compound in biochemical and pharmacological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	(5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine Hydrochloride
CAS No.	2703756-83-4
Molecular Formula	C10H12BrClFN
Molecular Weight	280.56 g/mol
Synonyms	1-(5-Bromo-2-fluorophenyl)-1-cyclopropylmethanamine hydrochloride; N-(5-Bromo-2-fluorobenzyl)cyclopropanamine hydrochloride; Cyclopropyl(5-bromo-2-fluorophenyl)methanamine HCl; (5-Bromo-2-fluoro-phenyl)-cyclopropyl-methyl-amine hydrochloride; 2703756-83-4; (Cyclopropyl)(5-bromo-2-fluorophenyl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.