Description

8-Quinolinecarboxamide, 5,6,7,8-Tetrahydro-n-Methyl- is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroquinoline class of compounds. This molecule matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific stereochemistry and functional groups are essential. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used in organic synthesis to introduce the tetrahydroquinoline pharmacophore, which is prevalent in compounds with biological activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Potential utility as a tool compound or inhibitor in biochemical and pharmacological assays.

Basic Information

Product Name	8-Quinolinecarboxamide, 5,6,7,8-Tetrahydro-n-Methyl-
CAS No.	2703752-93-4
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	N-Methyl-5,6,7,8-tetrahydroquinoline-8-carboxamide; 5,6,7,8-Tetrahydro-N-methylquinoline-8-carboxamide; 8-Carbamoyl-N-methyl-1,2,3,4-tetrahydroquinoline; Tetrahydro-N-methyl-8-quinolinecarboxamide
EINECS	Contact for details

Quality Control

Our 8-Quinolinecarboxamide, 5,6,7,8-Tetrahydro-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.