Description

2-Thiophenemethanamine, 4-Bromo-α-Methyl-, Hydrochloride (1:1), (αs)- is a high-purity, chiral organic building block of significant interest in advanced pharmaceutical synthesis. This compound matters as a key intermediate for developing novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. Research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries need this specific chiral amine for constructing complex molecular architectures with precise stereochemistry.

Application

• Critical chiral intermediate in the research and development of novel pharmaceutical candidates.
• Building block for the synthesis of complex molecules in medicinal chemistry and drug discovery programs.
• Precursor for ligands and catalysts used in asymmetric synthesis.
• Key starting material for the development of agrochemicals and other bioactive compounds.
• Used in academic and industrial research for exploring structure-activity relationships (SAR).
• Intermediate in the synthesis of advanced materials and functionalized heterocycles.

Basic Information

Product Name	2-Thiophenemethanamine, 4-Bromo-α-Methyl-, Hydrochloride (1:1), (αs)-
CAS No.	2682097-56-7
Molecular Formula	C6H9BrClNS
Molecular Weight	226.56 g/mol
Synonyms	(αS)-4-Bromo-α-methyl-2-thiophenemethanamine hydrochloride; (S)-4-Bromo-α-methylthiophene-2-methanamine hydrochloride; 4-Bromo-α-methyl-2-thiopheneethanamine hydrochloride (S-enantiomer); (2S)-1-(4-Bromothiophen-2-yl)ethan-1-amine hydrochloride; 4-Bromo-α-methyl-2-thiophenemethylamine hydrochloride; Bromothiophene methylamine hydrochloride derivative; Chiral bromothiophene amine salt
EINECS	Contact for details

Quality Control

Our 2-Thiophenemethanamine, 4-Bromo-α-Methyl-, Hydrochloride (1:1), (αs)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. The product undergoes rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.