Description

(R)-2-Aminonon-8-Enoic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative featuring a terminal alkene group. This chiral building block is critical for the synthesis of complex bioactive molecules, offering a unique handle for further functionalization via click chemistry or cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and process chemistry teams for the development of novel peptide-based therapeutics, enzyme inhibitors, and other advanced chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide mimetics and constrained analogs.
• Peptidomimetic Synthesis: Used to introduce non-natural amino acid residues into peptide chains to enhance metabolic stability, bioavailability, and binding affinity.
• Chemical Biology Probe Development: The terminal alkene moiety serves as a versatile site for bioconjugation via thiol-ene or other bioorthogonal reactions, enabling the creation of labeled probes.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical space and optimize lead compounds.
• Asymmetric Synthesis Building Block: Utilized in the preparation of enantiomerically pure compounds for catalysis and material science applications.

Basic Information

Product Name	(R)-2-Aminonon-8-Enoic Acid Hydrochloride
CAS No.	2682097-51-2
Molecular Formula	C9H18ClNO2
Molecular Weight	207.70 g/mol
Synonyms	(R)-2-Amino-8-nonenoic acid hydrochloride; (R)-8-Nonen-2-amine-1-carboxylic acid hydrochloride; (2R)-2-Aminonon-8-enoic acid hydrochloride; D-2-Aminonon-8-enoic acid HCl; (R)-Homoallylglycine hydrochloride; (R)-2-Amino-8-nonenoic acid HCl salt; Non-proteinogenic amino acid derivative
EINECS	Contact for details

Quality Control

Our (R)-2-Aminonon-8-Enoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.