Description

(S)-1-(2-Chloro-4-Methylphenyl)Ethan-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a defined stereocenter essential for developing active pharmaceutical ingredients (APIs) and other fine chemicals with specific enantiomeric requirements. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel therapeutic agents and high-value chemical products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used as a building block for creating enantiomerically pure herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Asymmetric Catalysis: Employed as a chiral ligand precursor or auxiliary in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials requiring specific optical activity.
• Academic & Industrial Research: Serves as a standard or starting material in methodological development and process chemistry research within organic and medicinal chemistry.

Basic Information

Product Name	(S)-1-(2-Chloro-4-Methylphenyl)Ethan-1-Amine Hydrochloride
CAS No.	2682097-28-3
Molecular Formula	C9H13Cl2N
Molecular Weight	206.11 g/mol (Free base: C9H12ClN)
Synonyms	(S)-1-(2-Chloro-4-methylphenyl)ethanamine hydrochloride
(S)-1-(2-Chloro-p-tolyl)ethylamine hydrochloride
(S)-α-Methyl-2-chloro-4-methylbenzylamine hydrochloride
(S)-2-Chloro-4-methyl-α-methylbenzylamine hydrochloride
(S)-1-(2-Chloro-4-methylphenyl)ethylamine HCl
(S)-1-Amino-1-(2-chloro-4-methylphenyl)ethane hydrochloride
CAS 2682097-28-3
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Chloro-4-Methylphenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profile is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.