Description

3-Oxabicyclo[3.1.0]Hexane-1-Methanamine, Hydrochloride (1:1), (1R,5S)- is a high-purity, stereochemically defined bicyclic amine hydrochloride salt, serving as a critical chiral building block in advanced organic synthesis. Its unique constrained oxabicyclo[3.1.0]hexane scaffold provides a rigid three-dimensional framework essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily utilized by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including potential therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used as a precursor for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a backbone for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with specific structural properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-Oxabicyclo[3.1.0]Hexane-1-Methanamine, Hydrochloride (1:1), (1R,5S)-
CAS No.	2682097-06-7
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	(1R,5S)-3-Oxabicyclo[3.1.0]hexane-1-methanamine hydrochloride; (1R,5S)-rel-3-Oxabicyclo[3.1.0]hexane-1-methanamine hydrochloride; endo-(1R,5S)-3-Oxabicyclo[3.1.0]hexan-1-ylmethanamine hydrochloride; Bicyclo[3.1.0]hexane, 3-oxa-1-methanamine, hydrochloride, (1R,5S)-; Chiral Oxabicyclohexylmethylamine HCl; (1R,5S)-3-Oxabicyclo[3.1.0]hexan-1-ylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Oxabicyclo[3.1.0]Hexane-1-Methanamine, Hydrochloride (1:1), (1R,5S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.