Description

3-Bromo-5-tert-Butylbenzofuran is a high-purity, halogenated benzofuran derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the tert-butyl and bromo functionalities.
• Material Science Precursor: Serves as a monomer or precursor for organic semiconductors, OLED materials, and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	3-Bromo-5-tert-Butylbenzofuran
CAS No.	2648402-53-1
Molecular Formula	C12H13BrO
Molecular Weight	253.14 g/mol
Synonyms	5-tert-Butyl-3-bromobenzofuran; 3-Bromo-5-(1,1-dimethylethyl)-1-benzofuran; 3-Bromo-5-tert-butyl-1-benzofuran; Benzofuran, 3-bromo-5-(1,1-dimethylethyl)-; 2648402-53-1; 3-Br-5-tBu-benzofuran
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-tert-Butylbenzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.