Description

Oxazole, 2,2'-[2-[4-(1,1-Dimethylethyl)Phenyl]-1-[[4-(1,1-Dimethylethyl)Phenyl]Methyl]Ethylidene]Bis[4,5-Dihydro-4-(Phenylmethyl)-, (4R,4'R)- is a sophisticated, stereochemically defined bis-oxazole derivative, serving as a high-value advanced pharmaceutical intermediate (API) and a critical building block in asymmetric synthesis. Its complex chiral structure makes it indispensable for the development of novel therapeutic agents, particularly in areas requiring precise molecular architecture. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex diseases.
• Asymmetric Catalysis Ligand: Potential use as a sophisticated ligand framework for transition metal catalysts in enantioselective transformations.
• Organic Synthesis Building Block: Employed in multi-step syntheses to construct complex natural product analogs and other high-value fine chemicals.
• Material Science Research: Investigation into its properties for potential applications in advanced organic electronic materials or specialty polymers.
• Agrochemical Intermediate: Exploration in the synthesis of new-generation, stereospecific crop protection agents.

Basic Information

Item	Details
Product Name	Oxazole, 2,2'-[2-[4-(1,1-Dimethylethyl)Phenyl]-1-[[4-(1,1-Dimethylethyl)Phenyl]Methyl]Ethylidene]Bis[4,5-Dihydro-4-(Phenylmethyl)-, (4R,4'R)-
CAS No.	2634687-81-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(4R,4'R)-2,2'-[2-[4-(tert-Butyl)Phenyl]-1-[[4-(tert-Butyl)Phenyl]Methyl]Ethylidene]Bis[4,5-Dihydro-4-Benzyloxazole]; Bis(4-Benzyl-4,5-dihydrooxazol-2-yl)(2-[4-(tert-butyl)phenyl]-1-([4-(tert-butyl)phenyl]methyl)ethylidene)methane, (4R,4'R)-; Chiral Bis(oxazoline) Derivative; (R,R)-Bis(4-benzyl-2-oxazoline) Ligand Analog; tert-Butyl-Substituted Chiral Bis-oxazoline; Advanced Chiral Auxiliary
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral intermediate adheres to stringent GMP (Good Manufacturing Practice) guidelines where applicable. Every batch undergoes comprehensive analytical characterization, including Chiral HPLC for enantiomeric excess (ee) verification, ¹H/¹³C NMR for structural confirmation, and mass spectrometry for identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is likely moisture-sensitive; handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container is opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.