Description

2,2'-Bipyridine, 6-[(4S)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]- is a sophisticated chiral ligand and building block, distinguished by its integration of a bipyridine core with a chiral oxazoline moiety. This molecular architecture is critical for applications requiring precise stereochemical control, particularly in asymmetric catalysis and the synthesis of advanced materials. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes and catalytic systems.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand for transition metal-catalyzed reactions, including asymmetric hydrogenation, cyclopropanation, and C–H functionalization.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) where chiral induction is required.
• Agrochemical Synthesis: Employed in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a functional component in the design of chiral metal-organic frameworks (MOFs) and luminescent materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Item	Detail
Product Name	2,2'-Bipyridine, 6-[(4S)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-
CAS No.	2634687-65-1
Molecular Formula	C16H19N3O
Molecular Weight	269.35 g/mol
Synonyms	(S)-6-(4-Isopropyl-4,5-dihydrooxazol-2-yl)-2,2'-bipyridine; (S)-2-(6-(Pyridin-2-yl)pyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole; Chiral Bipyridine-Oxazoline Ligand; (S)-iPr-Box; (S)-2,2'-Bipyridyl-6-yl-4-isopropyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.