Description

(S)-1-(4-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for the development of enantiomerically pure active pharmaceutical ingredients (APIs), where the specific (S)-configuration is essential for biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry research for lead optimization and the creation of novel chemical entities.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in stereoselective chemical reactions.
• Agrochemical Research: Potential intermediate in the development of advanced, optically active pesticides and herbicides.
• Ligand Synthesis: Precursor for creating chiral ligands used in catalysis.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-1-(4-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride
CAS No.	2633638-66-9
Molecular Formula	C8H10Cl2FN
Molecular Weight	210.08 g/mol
Synonyms	(S)-1-(4-Chloro-2-fluorophenyl)ethanamine hydrochloride; (S)-α-Methyl-4-chloro-2-fluorobenzylamine hydrochloride; (S)-1-(4-Chloro-2-fluorophenyl)ethylamine HCl; (S)-4-Chloro-2-fluoro-α-methylbenzylamine hydrochloride; (S)-1-Aminoethyl-4-chloro-2-fluorobenzene hydrochloride; (S)-1-(4-Chloro-2-fluorophenyl)ethan-1-amine HCl; (S)-1-(4-Chloro-2-fluorophenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.