Description

3-Cyclopropylpyrrolidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern synthetic chemistry. Its value lies in its unique bicyclic amine structure, which serves as a critical scaffold for constructing novel bioactive molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of complex active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, leveraging its constrained cyclopropyl-pyrrolidine framework.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of molecular probes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Cyclopropylpyrrolidine Hydrochloride
CAS No.	2612096-70-3
Molecular Formula	C7H14ClN
Molecular Weight	147.65 g/mol
Synonyms	3-Cyclopropylpyrrolidine HCl; Pyrrolidine, 3-cyclopropyl-, hydrochloride; 3-Cyclopropylpyrrolidine hydrochloride; 3-Cyclopropyl-1-azacyclopentane hydrochloride; (R/S)-3-Cyclopropylpyrrolidine hydrochloride; Cyclopropylpyrrolidine hydrochloride; 1-Azabicyclo[3.1.0]hexane hydrochloride (tautomer); 2612096-70-3
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylpyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), chiral purity (if applicable), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, the container must be kept in a cool, dry place. For long-term storage, maintain at 2-8°C under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.