Description

1,5-Naphthyridin-2(1H)-One, 7-(Bromomethyl)-3-Ethyl- is a high-value, functionalized naphthyridinone derivative designed for advanced chemical synthesis. This compound matters as a versatile and critical building block, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: The reactive bromomethyl group allows for conjugation, making it useful for creating labeled compounds and molecular probes.
• Material Science Precursor: Acts as a building block for organic electronic materials and advanced polymers requiring specific nitrogen-containing heterocycles.
• Cross-Coupling Reactions: The bromine atom facilitates various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Library Synthesis for HTS: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	1,5-Naphthyridin-2(1H)-One, 7-(Bromomethyl)-3-Ethyl-
CAS No.	2589531-82-6
Molecular Formula	C11H11BrN2O
Molecular Weight	267.12 g/mol
Synonyms	7-(Bromomethyl)-3-ethyl-1,5-naphthyridin-2(1H)-one; 3-Ethyl-7-(bromomethyl)-1,5-naphthyridin-2(1H)-one; 7-(Bromomethyl)-3-ethyl-1,5-dihydro-2H-1,5-naphthyridin-2-one; 1,5-Naphthyridin-2(1H)-one, 7-(bromomethyl)-3-ethyl-; 2589531-82-6; 3-Ethyl-7-(bromomethyl)-1H-1,5-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 1,5-Naphthyridin-2(1H)-One, 7-(Bromomethyl)-3-Ethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.