Description

1,7-Naphthyridine-3-Carboxylic Acid, 5,6,7,8-Tetrahydro-, Methyl Ester, Hydrochloride (1:2) is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for pharmaceutical research, particularly in the development of novel active pharmaceutical ingredients (APIs) and drug candidates targeting complex biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug molecules, particularly those with naphthyridine-based core structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering novel therapeutic agents.
• Chemical Biology Probe Synthesis: Employed in the creation of specialized molecular probes for studying enzyme mechanisms and biological pathways.
• Agrochemical Development: Acts as a building block for synthesizing advanced crop protection agents and pesticides.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Institutional Research: Supports chemical research in universities and institutes focused on heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	1,7-Naphthyridine-3-Carboxylic Acid, 5,6,7,8-Tetrahydro-, Methyl Ester, Hydrochloride (1:2)
CAS No.	2551116-71-1
Molecular Formula	C10H12N2O2 · 2HCl
Molecular Weight	273.13 g/mol (Free base: 192.22 g/mol)
Synonyms	5,6,7,8-Tetrahydro-1,7-naphthyridine-3-carboxylic acid methyl ester dihydrochloride; Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride (1:2); 1,7-Naphthyridine-3-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester, hydrochloride; Tetrahydro-1,7-naphthyridine-3-methyl carboxylate di-HCl; 3-(Methoxycarbonyl)-5,6,7,8-tetrahydro-1,7-naphthyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,7-Naphthyridine-3-Carboxylic Acid, 5,6,7,8-Tetrahydro-, Methyl Ester, Hydrochloride (1:2) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with full analytical data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.