Description

1H-Benzimidazole-2-Methanamine, α-Methyl-, Hydrochloride (1:2), (αr)- is a high-purity chiral benzimidazole derivative supplied as a dihydrochloride salt. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis and organic chemistry research. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in oncology and antiviral therapies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Intermediate in the synthesis of novel, targeted pesticides and herbicides requiring specific stereochemistry for efficacy.
• Fine Chemical Production: Building block for creating complex, high-value specialty chemicals used in material science and electronics.
• Biochemical Tool Compound: Used in life science research to study enzyme inhibition and receptor binding where stereochemistry is a factor.
• Academic & Industrial R&D: Fundamental material for methodological development in organic synthesis and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	1H-Benzimidazole-2-Methanamine, α-Methyl-, Hydrochloride (1:2), (αr)-
CAS No.	2503155-57-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(αR)-α-Methyl-1H-benzimidazole-2-methanamine dihydrochloride; (R)-1-(1H-Benzo[d]imidazol-2-yl)ethan-1-amine dihydrochloride; (R)-2-(1-Aminoethyl)-1H-benzimidazole dihydrochloride; AR-α-Methyl-1H-benzimidazole-2-methanamine dihydrochloride; Chiral Benzimidazole Ethylamine Dihydrochloride; (R)-1H-Benzimidazole-2-ethanamine, α-methyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and chiral integrity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific results for chiral purity (enantiomeric excess), chemical purity, and related substances are available upon request. We adhere to cGMP principles for manufacturing and quality management where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.