Description

1-(2-Chlorophenyl)-2,2,2-Trifluoroethanamine Hcl CAS NO 2490705-16-1 is a high-purity, halogenated amine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy and environmental stability.
• Chemical Research: Serves as a versatile precursor in academic and industrial R&D for exploring new reaction pathways and creating complex molecular architectures.
• Ligand and Catalyst Development: The amine functionality makes it suitable for developing novel ligands for metal catalysis and organocatalysts.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with unique fluorinated properties.

Basic Information

Product Name	1-(2-Chlorophenyl)-2,2,2-Trifluoroethanamine Hydrochloride
CAS No.	2490705-16-1
Molecular Formula	C8H8ClF3N • HCl
Molecular Weight	250.51 g/mol
Synonyms	1-(2-Chlorophenyl)-2,2,2-trifluoroethanamine hydrochloride; 2-Chloro-α-(trifluoromethyl)benzylamine hydrochloride; 1-(2-Chlorophenyl)-2,2,2-trifluoroethylamine HCl; (2-Chlorophenyl)(trifluoromethyl)methanamine hydrochloride; α-(Trifluoromethyl)-2-chlorobenzylamine hydrochloride; 2-Chloro-α,α,α-trifluoroethylbenzylamine hydrochloride; 1-(2-Chlorophenyl)-2,2,2-trifluoroethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-2,2,2-Trifluoroethanamine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.