Description

3-Quinolinecarboxylic Acid, 7-[(4As,7As)-1-(2-Carboxyethyl)Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-4-Oxo- is a high-purity, structurally complex advanced pharmaceutical intermediate. This compound is critical for research and development in the synthesis of novel antibacterial agents, particularly within the fluoroquinolone class. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise molecular architecture for next-generation drug candidates. Our supply ensures the consistent quality and traceability essential for regulatory filings and scale-up processes.

Application

• Key Intermediate in Novel Antibiotic Synthesis: Serves as a critical building block in the research and development of new-generation fluoroquinolone antibiotics.
• Pharmaceutical R&D: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs targeting bacterial infections.
• Process Chemistry & Scale-Up: Employed in route scouting and pilot-scale production for potential Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Manufacturing: Supplied to contract research and manufacturing organizations (CROs/CMOs) specializing in complex heterocyclic compounds.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Used in university and institutional labs studying antibacterial mechanisms and novel synthetic methodologies.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[(4As,7As)-1-(2-Carboxyethyl)Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-4-Oxo-
CAS No.	2489671-20-5
Molecular Formula	C24H28FN3O6
Molecular Weight	473.50 g/mol
Synonyms	7-[(4As,7As)-1-(2-Carboxyethyl)octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid; Advanced Fluoroquinolone Intermediate; (4As,7As)-6-(1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-3-yl)-1,2,3,4,4a,5,7,7a-octahydro-6H-pyrrolo[3,4-b]pyridine-7-carboxylic acid derivative; Complex Quinolone-Pyrrolopyridine Hybrid; Antibacterial Research Intermediate
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We employ state-of-the-art analytical techniques including HPLC, LC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.