Description

1-Bromo-3,4-Difluoro-5-Iodo-2-Methoxybenzene is a highly functionalized, multi-halogenated benzene derivative designed for advanced synthetic chemistry. This compound serves as a critical, multi-functional building block for constructing complex molecular architectures, offering multiple orthogonal reactive sites for sequential functionalization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as drug discovery, ligand synthesis, and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: A versatile synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis and molecular recognition.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and mechanisms.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-Bromo-3,4-Difluoro-5-Iodo-2-Methoxybenzene
CAS No.	2484889-22-5
Molecular Formula	C7H4BrF2IO
Molecular Weight	348.91 g/mol
Synonyms	2-Bromo-4,5-Difluoro-6-Iodo-1-Methoxybenzene; 3,4-Difluoro-5-Iodo-2-Methoxybromobenzene; Benzene, 1-bromo-3,4-difluoro-5-iodo-2-methoxy-; 1-Bromo-3,4-difluoro-5-iodo-2-methoxybenzene; 2-Methoxy-3,4-difluoro-5-iodobromobenzene; 5-Iodo-1-bromo-3,4-difluoro-2-methoxybenzene; 4,5-Difluoro-6-iodo-2-methoxybromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,4-Difluoro-5-Iodo-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.