Description

(R)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its enantiomeric purity, which is critical for the development of active pharmaceutical ingredients (APIs) and advanced organic synthesis. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for metal-catalyzed reactions and organocatalysts.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride
CAS No.	2453297-12-4
Molecular Formula	C8H10N2O3 • HCl
Molecular Weight	218.63 (Free base) / 255.09 (HCl salt)
Synonyms	(R)-2-Amino-2-(3-nitrophenyl)ethanol hydrochloride; (R)-2-Amino-2-(3-nitrophenyl)ethan-1-ol hydrochloride; (R)-2-(3-Nitrophenyl)glycinol hydrochloride; (R)-3-Nitro-β-phenylglycinol hydrochloride; (R)-2-(3-Nitrobenzyl)aminoethanol hydrochloride; (R)-1-(3-Nitrophenyl)-2-aminoethanol hydrochloride; (R)-2-(3-Nitrophenyl)-2-aminoethanol hydrochloride; (R)-3-Nitro-D-phenylglycinol hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.