Description

(S)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride is a high-purity chiral building block essential for advanced pharmaceutical synthesis and fine chemical research. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to incorporate a specific enantiomeric configuration into their molecular designs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Serves as a precursor in the synthesis of novel, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands for metal-catalyzed transformations.
• Academic & Institutional Research: A valuable compound for studying stereochemistry, reaction mechanisms, and developing new synthetic methodologies in university and government laboratories.
• Peptidomimetics: The structural motif can be incorporated into peptide analogs to enhance stability and biological activity.

Basic Information

Product Name	(S)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride
CAS No.	2453296-88-1
Molecular Formula	C8H10N2O3 • HCl
Molecular Weight	218.63 (Free base) / 255.09 (HCl salt)
Synonyms	(S)-2-Amino-2-(3-nitrophenyl)ethanol hydrochloride; (S)-2-Amino-2-(3-nitrophenyl)ethan-1-ol HCl; (S)-2-Amino-2-(m-nitrophenyl)ethanol hydrochloride; (S)-3-Nitro-β-amino-phenethyl alcohol hydrochloride; (S)-2-Amino-1-(3-nitrophenyl)ethanol hydrochloride; (S)-1-(3-Nitrophenyl)-2-aminoethanol hydrochloride; (S)-2-(3-Nitrophenyl)glycinol hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(3-Nitrophenyl)Ethan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (typically >99% ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.