Description

1,3-Benzoxaphosphole, 3-(1,1-Dimethylethyl)-2,3-dihydro-4-(2-methoxyphenyl)-, (3S)- is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a sophisticated building block or ligand for the development of novel pharmaceuticals and specialty materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require precise, enantiomerically pure intermediates. The compound is supplied with a CAS Number of 2448646-14-6.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or antiviral drug candidates.
• Asymmetric Catalysis: Serves as a potential ligand or precursor for chiral catalysts used in enantioselective synthesis, enhancing the efficiency of creating single-isomer compounds.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides or herbicides where specific stereochemistry is critical for bioactivity.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for method development and exploring new reaction pathways in organophosphorus and heterocyclic chemistry.

Basic Information

Product Name	1,3-Benzoxaphosphole, 3-(1,1-Dimethylethyl)-2,3-dihydro-4-(2-methoxyphenyl)-, (3S)-
CAS No.	2448646-14-6
Molecular Formula	C19H23O2P
Molecular Weight	314.36 g/mol
Synonyms	(3S)-3-(tert-Butyl)-4-(2-methoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphole; (S)-3-(tert-Butyl)-4-(2-methoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; 3S-Benzoxaphosphole derivative; tert-Butyl-substituted benzoxaphosphole; Chiral benzoxaphosphole ligand precursor; 2-Methoxyphenyl-dihydrobenzoxaphosphole
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, chiral excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.