Description

1-Pentanone, 2-Amino-4-Methyl-1-[(2S)-2-Methyl-2-Oxiranyl]-, (2R)-Rel-, 2,2,2-Trifluoroacetate (1:1) is a specialized chiral building block and advanced pharmaceutical intermediate of significant synthetic interest. This compound is valued for its complex molecular architecture, featuring both amino and oxiranyl (epoxide) functional groups, which makes it a versatile precursor in stereoselective synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex, stereochemically defined molecules.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a critical starting material or intermediate in structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other performance materials requiring specific stereochemistry.
• Academic & Industrial R&D: Used in chemical research laboratories for developing new synthetic methodologies and exploring novel chemical spaces.

Basic Information

Product Name	1-Pentanone, 2-Amino-4-Methyl-1-[(2S)-2-Methyl-2-Oxiranyl]-, (2R)-Rel-, 2,2,2-Trifluoroacetate (1:1)
CAS No.	2436762-87-5
Molecular Formula	C13H20F3NO4
Molecular Weight	311.30 g/mol
Synonyms	(2R)-rel-2-Amino-4-methyl-1-[(2S)-2-methyloxiran-2-yl]pentan-1-one; 2,2,2-Trifluoroacetate; 2-Amino-4-methyl-1-[(2S)-2-methyl-2-oxiranyl]pentan-1-one (2R)-rel- Trifluoroacetate; 1-Pentanone, 2-amino-4-methyl-1-[(2S)-2-methyl-2-oxiranyl]-, (2R)-rel-, 2,2,2-trifluoroacetate; Chiral Amino Epoxide Trifluoroacetate Salt; Advanced Chiral Synthon; TFA Salt of Amino Epoxide Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and chiral purity. Quality is assured through modern analytical techniques including HPLC, GC, NMR, and chiral analysis. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.