Description

H2N-Peg7-Ch2Ch2Cootbu is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a primary amine group and a tert-butyl ester-protected carboxylic acid. This compound is engineered to serve as a versatile, water-soluble linker for bioconjugation and the development of advanced drug delivery systems. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and stable crosslinking for peptides, proteins, and other bioactive molecules.

Application

• Bioconjugation Linker: For coupling peptides, proteins, antibodies, or oligonucleotides to surfaces, nanoparticles, or other biomolecules.
• ADC (Antibody-Drug Conjugate) Development: As a key component in constructing stable, cleavable, or non-cleavable linkers between cytotoxic payloads and monoclonal antibodies.
• PEGylation Reagent: To introduce hydrophilic PEG chains onto drugs or proteins, improving solubility, stability, and pharmacokinetic profiles.
• Functionalized Nanoparticle Synthesis: For surface modification of liposomes, polymeric nanoparticles, or quantum dots to enable targeted delivery.
• Hydrogel and Biomaterial Fabrication: As a crosslinking agent to create biocompatible matrices for tissue engineering and controlled release applications.
• Diagnostic Probe Synthesis: In the preparation of fluorescent or other labeled probes for imaging and assay development.

Basic Information

Product Name	H2N-Peg7-Ch2Ch2Cootbu
CAS No.	2428400-07-9
Molecular Formula	C31H63NO13
Molecular Weight	657.8 g/mol
Synonyms	Amine-PEG7-t-butyl ester; 2,5,8,11,14,17,20-Heptaoxadocosan-22-oic acid, 22-amino-4,4-dimethyl-3,21-dioxo-1,24-diyl t-butyl ester; α-Amino-ω-(t-butoxycarbonyl)heptaethylene glycol; Boc-NH-PEG7-COOH (t-butyl ester); 8-Amino-3,6,9,12,15,18,21-heptaoxatricosanoic acid tert-butyl ester; Amino-PEG7-acid t-butyl ester; Heterobifunctional PEG Amine t-Butyl Ester (PEG7); tert-Butyl 22-amino-3,21-dioxo-2,5,8,11,14,17,20-heptaoxa-4-azatricosan-24-oate
EINECS	Contact for details

Quality Control

Our H2N-Peg7-Ch2Ch2Cootbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) with detailed specifications to ensure the material meets the stringent requirements for research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.