Description

7-Azabicyclo[4.1.0]Hept-3-Ene-3-Carboxylic Acid, 7-(1,1-Dimethylethyl)-5-(1-Ethylpropoxy)-, Ethyl Ester, (1R,5R,6R)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for efficacy and safety. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Process Chemistry Development: Serves as a critical chiral precursor in scaling up synthetic routes from laboratory to pilot and commercial production.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials and commercial APIs.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations.

Basic Information

Product Name	7-Azabicyclo[4.1.0]Hept-3-Ene-3-Carboxylic Acid, 7-(1,1-Dimethylethyl)-5-(1-Ethylpropoxy)-, Ethyl Ester, (1R,5R,6R)-
CAS No.	2417645-75-9
Molecular Formula	C17H29NO3
Molecular Weight	295.42 g/mol
Synonyms	(1R,5R,6R)-7-(tert-Butyl)-5-(1-ethylpropoxy)-7-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester; Ethyl (1R,5R,6R)-7-tert-butyl-5-(1-ethylpropoxy)-7-azabicyclo[4.1.0]hept-3-ene-3-carboxylate; 7-tert-Butyl-5-(1-ethylpropoxy)-7-azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester; (1R,5R,6R)-7-Azabicyclo[4.1.0]hept-3-ene-3-carboxylic acid, 7-(1,1-dimethylethyl)-5-(1-ethylpropoxy)-, ethyl ester; CAS 2417645-75-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. All batches are characterized and tested to meet stringent specifications suitable for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We adhere to a quality management system designed to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.