Description

Pyridine, 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-(Diphenylmethyl)- is a high-value, chiral heterocyclic compound featuring a complex pyridine-oxazoline-diphenylmethyl architecture. This sophisticated structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile chiral ligand or catalyst precursor in asymmetric synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active ingredients, particularly for applications in oncology, neurology, and other therapeutic areas requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs), especially those targeting specific biological pathways.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective transformations, such as hydrogenations, oxidations, and C-C bond formations.
• Medicinal Chemistry Research: Employed in drug discovery and development programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, chiral crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or functional component in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	Pyridine, 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-(Diphenylmethyl)-
CAS No.	2417528-06-2
Molecular Formula	C27H22N2O
Molecular Weight	390.48 g/mol
Synonyms	6-(Diphenylmethyl)-2-[(4S)-4,5-dihydro-4-phenyl-2-oxazolyl]pyridine; (S)-6-(Diphenylmethyl)-2-(4,5-dihydro-4-phenyloxazol-2-yl)pyridine; (4S)-6-(Diphenylmethyl)-2-(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine; Chiral Pyridine-Oxazoline Ligand Precursor; CAS 2417528-06-2
EINECS	Contact for details

Quality Control

This high-purity specialty chemical is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) are provided, detailing results from HPLC, chiral analysis, NMR, and other relevant tests. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.