Description

(4R,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole is a chiral oxazoline derivative of significant interest in advanced organic synthesis. This compound matters as a high-value building block and potential ligand for asymmetric catalysis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel synthetic pathways and catalytic processes.

Application

• As a chiral ligand or precursor for metal-catalyzed asymmetric synthesis reactions.
• As a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• In the synthesis of complex natural products and fine chemicals requiring high stereoselectivity.
• For methodological development in organic chemistry and catalysis research.
• As a building block for advanced materials with specific optical properties.
• In the preparation of specialized catalysts for industrial-scale enantioselective manufacturing.

Basic Information

Item	Details
Product Name	(4R,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole
CAS No.	2417321-38-9
Molecular Formula	C24H18N2O
Molecular Weight	350.42 g/mol
Synonyms	(4R,5R)-4,5-Diphenyl-2-(quinolin-2-yl)-4,5-dihydro-1,3-oxazole; (4R,5R)-2-(Quinolin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole; (R,R)-2-(2-Quinolyl)-4,5-diphenyl-2-oxazoline; Chiral Quinoline-Oxazoline Ligand; (R,R)-Quinox Ligand; (4R,5R)-DPQO; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (4R,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.