Description

(4R,5S)-2-(6-Methylpyridin-2-Yl)-4,5-Diphenyl-4,5-Dihydrooxazole is a high-value, chiral oxazoline derivative that serves as a critical building block and ligand in advanced organic synthesis. Its precise stereochemistry and rigid structure make it an essential component for developing asymmetric catalysts and novel pharmaceutical intermediates. This compound is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemical development, and materials science.

Application

• Asymmetric Catalysis: Employed as a chiral ligand in transition metal-catalyzed reactions, such as hydrogenation, cyclopropanation, and cross-coupling, to induce high enantioselectivity.
• Pharmaceutical Intermediates: A key precursor in the synthesis of complex, biologically active molecules for drug discovery and development programs.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Material Science: Serves as a monomer or additive for creating chiral polymers and advanced functional materials with specific optical properties.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and reaction mechanisms in organic chemistry.

Basic Information

Product Name	(4R,5S)-2-(6-Methylpyridin-2-Yl)-4,5-Diphenyl-4,5-Dihydrooxazole
CAS No.	2417321-37-8
Molecular Formula	C21H18N2O
Molecular Weight	314.38 g/mol
Synonyms	(4R,5S)-4,5-Diphenyl-2-(6-methyl-2-pyridinyl)-4,5-dihydrooxazole; (4R,5S)-2-(6-Methyl-2-pyridyl)-4,5-diphenyl-4,5-dihydrooxazole; (4R,5S)-4,5-Diphenyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole; Chiral Oxazoline Ligand; Pyridine-Substituted Dihydrooxazole; (4R,5S)-Oxazoline Derivative
EINECS	Contact for details

Quality Control

Our (4R,5S)-2-(6-Methylpyridin-2-Yl)-4,5-Diphenyl-4,5-Dihydrooxazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.