Description

2-Buten-1-Amine, 3-Fluoro-4-(8-Quinolinylsulfonyl)-, Hydrochloride, Hydrate (1:2:1), (2Z)- is a high-purity, structurally complex organic salt designed for advanced research and development. This compound is valued for its unique molecular architecture, combining a fluorinated butenamine backbone with a quinolinylsulfonyl moiety, making it a critical intermediate in pharmaceutical discovery. It is primarily sought by researchers and process chemists in the life sciences sector for the synthesis of novel bioactive molecules and as a key building block in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated building block in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated and sulfonated functional groups.
• Biochemical Probe Development: Acts as a precursor for creating specialized probes and inhibitors to study enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale synthesis of complex drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and chemical biology.

Basic Information

Product Name	2-Buten-1-Amine, 3-Fluoro-4-(8-Quinolinylsulfonyl)-, Hydrochloride, Hydrate (1:2:1), (2Z)-
CAS No.	2414974-55-1
Molecular Formula	C₁₃H₁₂FN₃O₂S • 2HCl • H₂O
Molecular Weight	Contact for details
Synonyms	(2Z)-3-Fluoro-4-(quinolin-8-ylsulfonyl)but-2-en-1-amine dihydrochloride monohydrate; 3-Fluoro-4-(8-quinolinesulfonyl)-2-buten-1-amine hydrochloride hydrate (1:2:1); (Z)-3-Fluoro-4-(quinolin-8-ylsulfonyl)but-2-en-1-amine dihydrochloride monohydrate; 2-Buten-1-amine, 3-fluoro-4-(8-quinolinylsulfonyl)-, hydrochloride, hydrate (1:2:1), (2Z)-; CAS 2414974-55-1; 8-Quinolinesulfonamide, N-[(1Z)-3-amino-1-fluoro-1-buten-1-yl]-, dihydrochloride, monohydrate
EINECS	Contact for details

Quality Control

Every batch of 2-Buten-1-Amine, 3-Fluoro-4-(8-Quinolinylsulfonyl)-, Hydrochloride, Hydrate (1:2:1), (2Z)- is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.