Description

2-Oxabicyclo[2.1.1]Hexane-1-Methanamine, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic ether scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules and active pharmaceutical ingredients (APIs). It serves as a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to explore new chemical spaces and develop innovative therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Medicinal Chemistry: Used in scaffold hopping and structure-activity relationship (SAR) studies due to its rigid, three-dimensional bicyclic structure.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides or insecticides with potentially new modes of action.
• Ligand and Catalyst Development: The amine functionality allows for use in creating novel chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Fine Chemical Synthesis: An advanced building block for the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]Hexane-1-Methanamine, Hydrochloride (1:1)
CAS No.	2413903-70-3
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	1-(Aminomethyl)-2-oxabicyclo[2.1.1]hexane hydrochloride; 2-Oxabicyclo[2.1.1]hexane-1-methanamine HCl; (1-Aminomethyl)-2-oxabicyclo[2.1.1]hexane hydrochloride; 2-Oxa-3-azabicyclo[2.1.1]hexane derivative (hydrochloride salt); Bicyclo[2.1.1]hexane, 1-(aminomethyl)-2-oxa-, hydrochloride; 2413903-70-3; 2-Oxabicyclo[2.1.1]hexan-1-ylmethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.1.1]Hexane-1-Methanamine, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.