Description

(R)-1-(3,5-Dichlorophenyl)Ethan-1-Aminehydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the three-dimensional architecture of target compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and catalysts where the (R)-enantiomer's specific spatial configuration is required for desired biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides, where the specific stereochemistry can enhance efficacy and reduce environmental impact.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis to create other single-enantiomer compounds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in asymmetric synthesis, structure-activity relationship (SAR) studies, and process chemistry optimization.
• Fine Chemical Production: An important intermediate for manufacturing other specialty and fine chemicals that require a defined (R)-configured amine backbone.

Basic Information

Product Name	(R)-1-(3,5-Dichlorophenyl)Ethan-1-Aminehydrochloride
CAS No.	2411591-66-5
Molecular Formula	C8H10Cl3N
Molecular Weight	234.53 g/mol
Synonyms	(R)-1-(3,5-Dichlorophenyl)ethylamine hydrochloride; (R)-α-Methyl-3,5-dichlorobenzylamine hydrochloride; (R)-3,5-Dichloro-α-methylbenzylamine HCl; (R)-1-(3,5-Dichlorophenyl)ethanamine hydrochloride; (R)-3,5-Dichloro-α-methylbenzylamine hydrochloride; (R)-1-Aminoethyl-3,5-dichlorobenzene hydrochloride; (R)-Amphetamine, 3,5-dichloro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(3,5-Dichlorophenyl)Ethan-1-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess (e.e.), and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.