Description

(R)-tert-Butyl Azepan-3-Ylcarbamate Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate, specifically the hydrochloride salt of a protected azepane derivative. This compound is of significant value for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a defined stereocenter critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• API Synthesis: Used in the multi-step synthesis of complex drug candidates, leveraging its protected amine functionality for selective reactions.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in the scale-up and optimization of manufacturing routes for chiral compounds under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Development: Potential use as an intermediate in the synthesis of advanced, chiral crop protection agents.

Basic Information

Product Name	(R)-tert-Butyl Azepan-3-Ylcarbamate Hydrochloride
CAS No.	2411591-22-3
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.80 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)azepane hydrochloride; (R)-tert-Butyl 3-aminoazepane-1-carboxylate hydrochloride; (R)-N-Boc-3-aminoazepane hydrochloride; (R)-1-Boc-3-aminoazepane HCl; Azepan-3-amine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrochloride, (3R)-; BOC-(R)-3-Aminoazepane Hydrochloride; (R)-3-(Boc-amino)azepane hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl Azepan-3-Ylcarbamate Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.