Description

(4S,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole is a high-value, chiral oxazoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated ligand or building block for the development of pharmaceuticals and fine chemicals, where its defined stereochemistry is critical for enantioselective catalysis and molecular recognition. It is primarily needed by research and development teams in pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on asymmetric synthesis, medicinal chemistry, and catalyst design.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation, cyclopropanation, and Diels-Alder reactions.
• As a key synthetic intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• In the preparation of advanced materials and functional polymers requiring specific stereochemical control.
• As a reference standard or analytical reagent for method development in chiral separation techniques (e.g., HPLC, SFC).
• For use in academic and industrial research exploring new reaction methodologies and organocatalysis.
• In the synthesis of complex natural products and bioactive molecules where the oxazoline moiety is a crucial structural element.

Basic Information

Product Name	(4S,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole
CAS No.	2411386-00-8
Molecular Formula	C24H18N2O
Molecular Weight	350.42 g/mol
Synonyms	(4S,5R)-4,5-Diphenyl-2-(quinolin-2-yl)-4,5-dihydro-1,3-oxazole; (S,R)-2-(2-Quinolyl)-4,5-diphenyl-2-oxazoline; (4S,5R)-2-(2-Quinolinyl)-4,5-diphenyl-4,5-dihydrooxazole; Chiral Quinoline-Oxazoline Ligand; (S,R)-Quinox Ligand; (4S,5R)-DQO; 2-(Quinolin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole (stereoisomer)
EINECS	Contact for details

Quality Control

Our (4S,5R)-4,5-Diphenyl-2-(Quinolin-2-Yl)-4,5-Dihydrooxazole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.