Description

4-Bromo-7-Methoxy-2,3-Dihydro-1H-Inden-1-Amine Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated indane structure. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other specialized small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly for neurological and oncological targets.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its reactive amine and bromo functional groups.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for developing new synthetic methodologies.
• Preclinical Drug Development: Used in the synthesis of compounds for pharmacological screening and early-stage toxicology studies.
• Chemical Reference Standard: Employed for analytical method development and validation, including HPLC and LC-MS, in quality control laboratories.

Basic Information

Product Name	4-Bromo-7-Methoxy-2,3-Dihydro-1H-Inden-1-Amine Hcl
CAS No.	2408958-29-0
Molecular Formula	C10H13BrClNO
Molecular Weight	278.57 g/mol
Synonyms	4-Bromo-7-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride; 1H-Inden-1-amine, 4-bromo-7-methoxy-2,3-dihydro-, hydrochloride (1:1); 4-Bromo-7-methoxyindan-1-amine HCl; 4-Bromo-7-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride salt; 2408958-29-0; 4-Br-7-MeO-indan-1-amine HCl
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Methoxy-2,3-Dihydro-1H-Inden-1-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.