Description

4-Bromo-3-Fluorophthalic Acid is a high-purity, multi-functional aromatic dicarboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated structure makes it an indispensable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen-substituted aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo-fluoro substitution pattern can enhance biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Polymer Chemistry: A monomer for the synthesis of specialized polyimides, polyesters, and other high-performance polymers with enhanced thermal stability and specific optical properties.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other electronic materials due to its electron-withdrawing halogen groups.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities.

Basic Information

Product Name	4-Bromo-3-Fluorophthalic Acid
CAS No.	2408642-17-9
Molecular Formula	C8H4BrFO4
Molecular Weight	263.02 g/mol
Synonyms	4-Bromo-3-fluorobenzene-1,2-dicarboxylic acid; 3-Fluoro-4-bromophthalic acid; 1,2-Benzenedicarboxylic acid, 4-bromo-3-fluoro-; 2408642-17-9; 4-Br-3-F-phthalic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorophthalic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.