Description

1H-Pyrrolizine-1,3(2H)-Dione, Tetrahydro-6-Hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19,26-Tetrahydroxy-2,4-Dimethyl-12-Hexacosen-1-Ylidene]-, (2Z,6R,7As)- is a complex, high-purity synthetic intermediate with a defined stereochemistry, identified by CAS No. 2396676-46-1. This compound is valued for its precise molecular architecture, making it a critical building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a reference standard or a probe molecule in studying biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Acts as a sophisticated building block for constructing complex natural product analogs and other specialty organic molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale under controlled GMP-like conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations requiring high-purity, structurally defined intermediates for custom synthesis projects.

Basic Information

Product Name	1H-Pyrrolizine-1,3(2H)-Dione, Tetrahydro-6-Hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19,26-Tetrahydroxy-2,4-Dimethyl-12-Hexacosen-1-Ylidene]-, (2Z,6R,7As)-
CAS No.	2396676-46-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2Z,6R,7aS)-6-Hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19,26-tetrahydroxy-2,4-dimethyl-12-hexacosen-1-ylidene]tetrahydro-1H-pyrrolizine-1,3(2H)-dione; Tetrahydro-6-hydroxy-2-[(2S,4R,12E,15R,19R)-1,15,19,26-tetrahydroxy-2,4-dimethyl-12-hexacosen-1-ylidene]-1H-pyrrolizine-1,3(2H)-dione; CAS 2396676-46-1; Advanced Pyrrolizinedione Intermediate; Chiral Pyrrolizine Derivative.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under stringent quality systems. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic (HPLC, UPLC) and spectroscopic (NMR, MS) methods. Our quality commitment aligns with cGMP principles for pharmaceutical starting materials, ensuring traceability, consistency, and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.