Description

(2-Ethynylphenyl)Methanamine Hydrochloride is a high-purity organic building block featuring a reactive ethynyl group and a primary amine hydrochloride salt. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in click chemistry and cross-coupling reactions. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs) via Huisgen cycloaddition (click chemistry) and Sonogashira coupling reactions.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that require acetylene-linked aromatic amine scaffolds.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Bioconjugation: Enables site-specific labeling and modification of biomolecules (proteins, nucleic acids) for diagnostic and therapeutic applications.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal complexation in industrial chemical processes.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(2-Ethynylphenyl)Methanamine Hydrochloride
CAS No.	2389017-90-5
Molecular Formula	C9H10ClN
Molecular Weight	167.63 g/mol
Synonyms	1-(2-Ethynylphenyl)methanamine hydrochloride; (2-Ethynylbenzyl)amine hydrochloride; 2-Ethynylbenzylamine hydrochloride; α-(2-Ethynylphenyl)methylamine hydrochloride; 2-Ethynylbenzenemethanamine hydrochloride; 1-(2-Ethynylphenyl)-N-methylmethanamine hydrochloride (common salt form); 2-Ethynylphenylmethylamine HCl
EINECS	Contact for details

Quality Control

Our (2-Ethynylphenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.