Description

(R)-1-(6-Methoxypyridin-3-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. Its core value lies in its role as a key intermediate for synthesizing active pharmaceutical ingredients (APIs) and other biologically active molecules, particularly those targeting neurological and metabolic disorders. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and manufacturing.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and metabolic disease drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in asymmetric synthesis to induce stereoselectivity in complex organic reactions.
• Medicinal Chemistry Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable, cost-effective synthetic routes for commercial drug production.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes, biomarkers, and bioconjugates for diagnostic and research applications.
• Fine Chemical Synthesis: A precursor for the manufacture of other specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(R)-1-(6-Methoxypyridin-3-Yl)Ethanamine Dihydrochloride
CAS No.	2389009-07-6
Molecular Formula	C8H14Cl2N2O
Molecular Weight	225.11 g/mol
Synonyms	(R)-1-(6-Methoxy-3-pyridinyl)ethanamine dihydrochloride; (R)-1-(6-Methoxypyridin-3-yl)ethan-1-amine dihydrochloride; (R)-α-Methyl-6-methoxy-3-pyridinemethanamine dihydrochloride; (R)-6-Methoxy-3-pyridineethanamine dihydrochloride; (R)-1-(6-Methoxypyridin-3-yl)ethylamine dihydrochloride; (R)-1-(6-Methoxy-pyridin-3-yl)-ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Methoxypyridin-3-Yl)Ethanamine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.