Description

8-Bromo-3-Fluoro-Naphthalene-1-Carboxylic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique halogenated naphthalene core, which provides distinct electronic and steric properties for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Serves as a precursor for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Used to synthesize specialized ligands for transition metal catalysis and organocatalysis in asymmetric synthesis.
• Material Science Research: A building block for organic semiconductors, liquid crystals, and photoactive materials in OLED and OFET development.
• Chemical Biology Probes: Employed in the design of fluorescent tags, molecular probes, and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	8-Bromo-3-Fluoro-Naphthalene-1-Carboxylic Acid
CAS No.	2387597-18-2
Molecular Formula	C11H6BrFO2
Molecular Weight	269.07 g/mol
Synonyms	8-Bromo-3-fluoronaphthalene-1-carboxylic acid; 1-Naphthalenecarboxylic acid, 8-bromo-3-fluoro-; 2387597-18-2; 8-Br-3-F-1-NA COOH; 3-Fluoro-8-bromo-1-naphthoic acid; 8-Bromo-3-fluoro-1-naphthoic acid; 1-Carboxy-8-bromo-3-fluoronaphthalene
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-3-Fluoro-Naphthalene-1-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC), identity (NMR, IR), and impurity profiles. Our quality commitment supports applications from early-stage discovery to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.