Description

5-(Prop-2-Yn-1-Yl)-1,2-Diazaspiro[2.3]Hex-1-Ene-5-Carboxylic Acid is a sophisticated spirocyclic diaza compound featuring a terminal alkyne functional group, making it a valuable high-purity building block for advanced chemical synthesis. Its unique molecular architecture is engineered to serve as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily targeted at pharmaceutical R&D and agrochemical research organizations seeking to incorporate complex, functionalized heterocycles into their molecular libraries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting spirocyclic scaffolds.
• Click Chemistry Reagent: The terminal alkyne moiety enables efficient Huisgen 1,3-dipolar cycloaddition (click chemistry) for bioconjugation and polymer functionalization.
• Agrochemical Research: Used in the discovery and development of new-generation herbicides and insecticides with novel modes of action.
• Material Science: Serves as a monomer or cross-linking agent for creating advanced polymers with tailored thermal and mechanical properties.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and protein-protein interactions.
• Library Synthesis for High-Throughput Screening: An essential building block for generating diverse compound libraries in drug discovery campaigns.

Basic Information

Product Name	5-(Prop-2-Yn-1-Yl)-1,2-Diazaspiro[2.3]Hex-1-Ene-5-Carboxylic Acid
CAS No.	2384877-68-1
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	5-(Prop-2-yn-1-yl)-1,2-diazaspiro[2.3]hex-1-ene-5-carboxylic acid; 1,2-Diazaspiro[2.3]hex-1-ene-5-carboxylic acid, 5-(2-propynyl)-; 5-(Prop-2-ynyl)-1,2-diazaspiro[2.3]hex-1-ene-5-carboxylic acid; Spiro[diaziridine-3,1'-cyclopropane]-3-carboxylic acid, 1'-(2-propynyl)-; CAS 2384877-68-1
EINECS	Contact for details

Quality Control

Our production of 5-(Prop-2-Yn-1-Yl)-1,2-Diazaspiro[2.3]Hex-1-Ene-5-Carboxylic Acid adheres to stringent cGMP and ISO 9001 quality management principles. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.