Description

4-Arm-Peg-Hydrazidehydrazide is a multi-functional, branched polyethylene glycol derivative terminated with reactive hydrazide groups. This molecular architecture is critical for creating stable, high-loading conjugates and cross-linked hydrogels with tailored properties. It is essential for researchers and manufacturers in the pharmaceutical and biomedical sectors who require precise, biocompatible linkers for drug delivery systems, bioconjugation, and advanced material science.

Application

• Bioconjugation and Drug Delivery: Serves as a versatile linker for attaching drugs, proteins, peptides, or targeting ligands via its multiple hydrazide termini, enabling the creation of multi-valent or high-payload conjugates.
• Hydrogel Formation: Acts as a cross-linking agent for synthesizing biocompatible and biodegradable hydrogels used in tissue engineering scaffolds, wound dressings, and controlled release matrices.
• Surface Functionalization: Used to modify nanoparticles, biosensors, and diagnostic devices to enhance biocompatibility and introduce specific reactive sites for further coupling.
• Polymer Chemistry: A key building block for synthesizing star-shaped or dendritic polymers with hydrophilic PEG arms, useful for creating novel carriers and materials.
• Diagnostic Reagent Preparation: Employed in the development of immunoassays and diagnostic kits by conjugating enzymes or fluorescent probes to antibodies or other biomolecules.

Basic Information

Product Name	4-Arm-Peg-Hydrazidehydrazide
CAS No.	2378802-50-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Four-Arm PEG Hydrazide; Tetra-Arm PEG-Hydrazide; 4-Arm-PEG-HZ; Poly(ethylene glycol) tetrahydrazide; PEG4-Hydrazide; Star-PEG Hydrazide; Multifunctional PEG Hydrazide; Tetrafunctional PEG Hydrazide
EINECS	Contact for details

Quality Control

Our 4-Arm-Peg-Hydrazidehydrazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and functional group analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and assay are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (NMR)	Complies
Purity (HPLC)	≥ 95%
Assay (Hydrazide Content)	≥ 90% of theoretical
Molecular Weight (GPC/SEC)	As per ordered specification (e.g., 2k, 5k, 10k Da)
Water Content (KF)	≤ 1.0%
Solvents (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.