Description

(S)-6-[3-(4-Boc-1-Piperazinyl)Propoxy]-n-[2-(2-Cyano-4,4-Difluoro-1-Pyrrolidinyl)-2-Oxoethyl]Quinoline-4-Carboxamide is a sophisticated, high-purity organic compound designed for advanced research and development. This molecule is a critical pharmaceutical intermediate, valued for its complex structure which incorporates key functional groups like a Boc-protected piperazine and a difluorinated pyrrolidinone. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Custom Synthesis: A starting material for the contract synthesis of more complex molecules for preclinical and clinical studies.
• Chemical Biology Probes: Potential use in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	(S)-6-[3-(4-Boc-1-Piperazinyl)Propoxy]-n-[2-(2-Cyano-4,4-Difluoro-1-Pyrrolidinyl)-2-Oxoethyl]Quinoline-4-Carboxamide
CAS No.	2374782-82-6
Molecular Formula	C₃₁H₃₆F₂N₆O₅
Molecular Weight	598.66 g/mol
Synonyms	(S)-6-[3-(4-Boc-1-Piperazinyl)Propoxy]-N-[2-(2-Cyano-4,4-Difluoro-1-Pyrrolidinyl)-2-Oxoethyl]Quinoline-4-Carboxamide; 2374782-82-6; tert-Butyl 4-[3-[[(S)-4-[[2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl]carbamoyl]quinolin-6-yl]oxy]propyl]piperazine-1-carboxylate; (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-6-(3-(4-(tert-butoxycarbonyl)piperazin-1-yl)propoxy)quinoline-4-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-6-[3-(4-Boc-1-Piperazinyl)Propoxy]-n-[2-(2-Cyano-4,4-Difluoro-1-Pyrrolidinyl)-2-Oxoethyl]Quinoline-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.