Description

1-Piperazinecarboxylic Acid, 4-(8-Bromo-4-Quinazolinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound matters as a critical building block in the development of novel, targeted therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds, particularly for oncology and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the discovery and development of novel anti-cancer agents targeting specific cellular pathways.
• Chemical Biology: Employed as a molecular probe or scaffold for studying protein-ligand interactions and enzyme functions.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Facilitates medicinal chemistry programs in universities and research institutes focused on heterocyclic chemistry.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(8-Bromo-4-Quinazolinyl)-, 1,1-Dimethylethyl Ester
CAS No.	2368909-93-5
Molecular Formula	C17H21BrN4O2
Molecular Weight	393.28 g/mol
Synonyms	tert-Butyl 4-(8-bromoquinazolin-4-yl)piperazine-1-carboxylate; 4-(8-Bromoquinazolin-4-yl)piperazine-1-carboxylic acid tert-butyl ester; 8-Bromo-4-(4-(tert-butoxycarbonyl)piperazin-1-yl)quinazoline; BOC-4-(8-Bromoquinazolin-4-yl)piperazine; 1-BOC-4-(8-bromo-4-quinazolinyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(8-bromoquinazolin-4-yl)piperazine
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 4-(8-Bromo-4-Quinazolinyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.