Description

4-((1S)-1-Aminopropyl)Phenol Hcl is a chiral organic compound featuring a phenol group and a primary amine functionality, presented as its hydrochloride salt for enhanced stability. This specific stereochemistry makes it a valuable chiral building block and intermediate in the synthesis of more complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Ligand and Catalyst Development: Used in the preparation of novel chiral ligands and organocatalysts for enantioselective transformations.
• Bioconjugation and Probe Synthesis: The amine and phenol groups provide handles for conjugation, useful in creating biochemical probes and labeled compounds for research.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of high-value agrochemicals, flavors, and fragrances.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	4-((1S)-1-Aminopropyl)Phenol Hcl
CAS No.	2368884-26-6
Molecular Formula	C9H14ClNO
Molecular Weight	187.67 g/mol
Synonyms	(S)-4-(1-Aminopropyl)phenol hydrochloride; (1S)-1-(4-Hydroxyphenyl)propylamine hydrochloride; 4-[(1S)-1-Aminopropyl]phenol hydrochloride; Phenol, 4-[(1S)-1-aminopropyl]-, hydrochloride; (S)-1-(4-Hydroxyphenyl)propan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-((1S)-1-Aminopropyl)Phenol Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.