Description

BrettPhos Pd G6 TES is a highly specialized, third-generation Buchwald precatalyst designed for superior performance in cross-coupling reactions. This product matters because it offers exceptional air and moisture stability, simplifying handling and storage compared to more sensitive phosphine ligands and palladium sources, which directly translates to more reliable and reproducible synthetic outcomes. It is critically needed by process chemists and researchers in the pharmaceutical, agrochemical, and advanced materials industries for the efficient synthesis of complex molecules, including active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling in API development.
• Agrochemical Manufacturing: Enables the construction of complex heterocyclic compounds used in crop protection agents.
• Materials Science Research: Facilitates the synthesis of conjugated polymers and organic electronic materials.
• Process Chemistry Optimization: Ideal for scaling up coupling reactions due to its stability and consistent activity.
• Academic & Industrial R&D: A preferred precatalyst for exploring new C-N, C-O, and C-C bond-forming methodologies.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring selective arylations.

Basic Information

Product Name	BrettPhos Pd G6 TES
CAS No.	2365275-34-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BrettPhos Palladacycle G6; Palladium G6 Precatalyst with BrettPhos; (2-Dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) TES complex; Pd-PEPPSI BrettPhos; Buchwald Precatalyst G6; Third-Generation BrettPhos Pd Precatalyst; Pd G6(BrettPhos) TES Salt
EINECS	Contact for details

Quality Control

Our BrettPhos Pd G6 TES is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous analytical testing, including NMR and HPLC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (argon or nitrogen) due to its sensitivity to moisture and oxygen. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.