Description

(S,R,S)-Ahpc-C10-Nh2 Dihydrochloride is a high-purity, chiral building block and pharmaceutical intermediate. This compound matters for its critical role in the synthesis of advanced, targeted therapeutic agents, particularly in oncology and other specialized research areas. It is needed by pharmaceutical R&D teams, process development chemists, and fine chemical manufacturers engaged in the production of novel drug candidates and proteolysis-targeting chimeras (PROTACs).

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for targeted protein degradation therapies.
• PROTACs Development: Serves as a crucial component (ligand or linker) in the design and construction of Proteolysis-Targeting Chimeras.
• Chemical Biology Research: Used as a tool compound for studying protein-protein interactions and cellular signaling pathways.
• Peptidomimetic Synthesis: Employed in the creation of stabilized peptide analogs with enhanced pharmacological properties.
• Oncology Research: Integral to the development of experimental cancer therapeutics that target specific oncoproteins.
• High-Value Fine Chemical Production: Manufactured under controlled conditions for use in cGMP and non-GMP pharmaceutical production streams.

Basic Information

Product Name	(S,R,S)-Ahpc-C10-Nh2 Dihydrochloride
CAS No.	2341796-75-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S,R,S)-Ahpc-C10-Amine Dihydrochloride; Ahpc-C10-NH2·2HCl; (2S,3R,4S)-4-Amino-1-((S)-2-amino-3,3-dimethylbutanoyl)-3-((S)-sec-butyl)-N-(10-amino-10-oxodecyl)pyrrolidine-2-carboxamide dihydrochloride; PROTAC Linker-Ligand Conjugate; (S,R,S)-Ahpc Decanamide Dihydrochloride; (S,R,S)-Ahpc-C10-NH2 2HCl; (S,R,S)-Ahpc-10-Amino-10-oxodecanamide Dihydrochloride
EINECS	Contact for details

Quality Control

Our (S,R,S)-Ahpc-C10-Nh2 Dihydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.