Description

(1R, 4R)-2,5-Diaza-Bicyclo[2.2.1]Heptane Dihydrochloride is a high-purity, chiral bicyclic diamine salt of significant interest in advanced organic synthesis. This compound serves as a critical, structurally constrained building block for the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the creation of new active pharmaceutical ingredients (APIs) and ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the synthesis of complex drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Ligand Synthesis: Used to prepare sophisticated chiral ligands for asymmetric catalysis, enhancing enantioselectivity in critical bond-forming reactions.
• Agrochemical Research: Employed in the development of new, more selective herbicides and pesticides with improved environmental profiles.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical space in discovery programs.

Basic Information

Product Name	(1R, 4R)-2,5-Diaza-Bicyclo[2.2.1]Heptane Dihydrochloride
CAS No.	2331211-51-7
Molecular Formula	C5H12N2 • 2HCl
Molecular Weight	197.09 g/mol
Synonyms	(1R,4R)-2,5-Diazabicyclo[2.2.1]heptane Dihydrochloride; (1R,4R)-2,5-Diazabicyclo[2.2.1]heptane Hydrochloride (1:2); (1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane Dihydrochloride; (1R,4R)-2,5-DABCO Dihydrochloride; endo-(1R,4R)-2,5-Diazabicyclo[2.2.1]heptane Dihydrochloride; (1R,4R)-2,5-Diazabicyclo[2.2.1]heptane, dihydrochloride; (1R,4R)-2,5-Diazabicyclo[2.2.1]heptane HCl salt
EINECS	Contact for details

Quality Control

Our (1R, 4R)-2,5-Diaza-Bicyclo[2.2.1]Heptane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.