Description

3-Pyridinecarboxamide, 2-Amino-5-[3-(1-Piperazinyl)Phenyl]-n-4-Pyridinyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant interest for its role as a key building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of targeted drug candidates. The precise molecular architecture offers a versatile scaffold for further chemical elaboration.

Application

• Critical intermediate in the synthesis of protein kinase inhibitors for oncology and inflammatory disease research.
• Building block for the development of small molecule drug candidates targeting specific enzymatic pathways.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Precursor in the custom synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical trials.
• Research chemical in academic and institutional laboratories studying heterocyclic chemistry and drug discovery.
• Starting material for the production of specialty fine chemicals and advanced organic compounds.

Basic Information

Product Name	3-Pyridinecarboxamide, 2-Amino-5-[3-(1-Piperazinyl)Phenyl]-n-4-Pyridinyl-
CAS No.	2328094-11-5
Molecular Formula	C21H22N6O
Molecular Weight	374.44 g/mol
Synonyms	2-Amino-5-[3-(1-piperazinyl)phenyl]-N-4-pyridinyl-3-pyridinecarboxamide; 2-Amino-N-(pyridin-4-yl)-5-[3-(piperazin-1-yl)phenyl]pyridine-3-carboxamide; 2328094-11-5; UNII-9K5F8V8A6T; 9K5F8V8A6T; 2-Amino-5-(3-piperazin-1-ylphenyl)-N-(pyridin-4-yl)nicotinamide; 4-Pyridinamine, N-[2-amino-5-[3-(1-piperazinyl)phenyl]-3-pyridinyl]-; AKOS040750623
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.