Description

Methyl 6-Bromo-8-Fluoro-Quinoline-3-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, particularly for oncology, antiviral, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated quinoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Employed as a molecular probe or a tagged scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and process development.

Basic Information

Product Name	Methyl 6-Bromo-8-Fluoro-Quinoline-3-Carboxylate
CAS No.	2306278-42-0
Molecular Formula	C11H7BrFNO2
Molecular Weight	284.08 g/mol
Synonyms	6-Bromo-8-fluoroquinoline-3-carboxylic acid methyl ester; Methyl 6-bromo-8-fluoro-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 6-bromo-8-fluoro-, methyl ester; 6-Bromo-8-fluoro-3-quinolinecarboxylic acid methyl ester; 2306278-42-0; Methyl 6-bromo-8-fluoroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromo-8-Fluoro-Quinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.