Description

(5S)-7-Oxa-2-Azaspiro[4.5]Decane Hemioxalate is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and spirocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative drugs, where precise molecular architecture is essential for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel neuroactive drugs and receptor modulators.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex spirocyclic and heterocyclic frameworks.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API manufacturing processes under GMP conditions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs for new chemical entities.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions due to its defined (5S) stereocenter.

Basic Information

Product Name	(5S)-7-Oxa-2-Azaspiro[4.5]Decane Hemioxalate
CAS No.	2306248-08-6
Molecular Formula	C9H15NO3 • 0.5(C2H2O4)
Molecular Weight	Contact for details
Synonyms	(5S)-7-Oxa-2-azaspiro[4.5]decane hemioxalate; (5S)-2-Aza-7-oxaspiro[4.5]decane hemioxalate; (5S)-7-Oxa-2-azaspiro[4.5]decane oxalic acid salt (1:0.5); (5S)-7-Oxa-2-azaspiro[4.5]decane hemi-oxalate; Spirocyclic oxazolidine hemioxalate; (5S)-2-Azaspiro[4.5]decan-7-one hemioxalate (tautomer); 2306248-08-6
EINECS	Contact for details

Quality Control

Our (5S)-7-Oxa-2-Azaspiro[4.5]Decane Hemioxalate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH Q7 guidelines for pharmaceutical intermediates, and our quality protocols are designed to meet the stringent requirements of GMP production environments for advanced APIs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.