Description

tert-Butyl (4-Bromo-1,5-Naphthyridin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a brominated naphthyridine core protected by a Boc (tert-butoxycarbonyl) group. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules targeting various therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncological Agent Development: Used in the construction of kinase inhibitors and other targeted cancer therapies due to the naphthyridine pharmacophore.
• Antiviral Compound Synthesis: Employed as a building block for molecules designed to interfere with viral replication mechanisms.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	tert-Butyl (4-Bromo-1,5-Naphthyridin-3-Yl)Carbamate
CAS No.	2288709-49-7
Molecular Formula	C₁₃H₁₄BrN₃O₂
Molecular Weight	332.18 g/mol
Synonyms	Boc-4-Bromo-1,5-naphthyridin-3-amine; tert-Butyl N-(4-bromo-1,5-naphthyridin-3-yl)carbamate; 4-Bromo-1,5-naphthyridin-3-amine, N-Boc-protected; 3-((tert-Butoxycarbonyl)amino)-4-bromo-1,5-naphthyridine; Boc-3-Amino-4-bromo-1,5-naphthyridine; 1,5-Naphthyridine, 4-bromo-3-[[(1,1-dimethylethoxy)carbonyl]amino]-; 2288709-49-7
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Bromo-1,5-Naphthyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.