Description

2,4,5,6-Tetrahydro-1H-Cyclobut[F]Inden-3-Amine is a specialized, high-purity amine derivative featuring a fused cyclobutane-indene core structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing new-generation pesticides and herbicides with unique modes of action.
• Ligand & Catalyst Development: Used to create complex chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	2,4,5,6-Tetrahydro-1H-Cyclobut[F]Inden-3-Amine
CAS No.	2271393-78-1
Molecular Formula	C11H13N
Molecular Weight	159.23 g/mol
Synonyms	Cyclobut[f]inden-3-amine, 2,4,5,6-tetrahydro-1H-; 1H-Cyclobut[f]inden-3-amine, 2,4,5,6-tetrahydro-; 2,4,5,6-Tetrahydro-1H-cyclobut[f]inden-3-amine; 3-Amino-2,4,5,6-tetrahydro-1H-cyclobut[f]indene; Tetrahydrocyclobut[f]inden-3-amine; Bicyclo[4.2.0]octa-1,3,5-trien-3-amine, 1,2,3,4-tetrahydro-; 2271393-78-1; Amine CBIA
EINECS	Contact for details

Quality Control

Our 2,4,5,6-Tetrahydro-1H-Cyclobut[F]Inden-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.